The requestor's "profession" (e.g., physician, pharmacist, nurse, lay person) should indicate educational experience and knowledge base; therefore, the individual receiving the query can use this information to determine the appropriate mannerism (in terms of educational level) to formulate and deliver the response.

For instance, a pharmacist is asked, "what is the dose of amoxicillin (Amoxil®)?" This question could be answered quickly (and potentially inaccurately) by stating that the normal dosage as 500 mg every eight hours. The question also could be answered by gathering background information concerning the origin of the question. A pharmacist would not provide the most commonly dispensed dose of amoxicillin as the dose for all individuals and conditions. The dose of this antibiotic depends upon a number of factors. Determine if the question is in regard to a specific patient or general research in the treatment of a disease state. If the question is patient specific, important information to acquire would include the patient's age, weight, allergies, type of infection, concurrent disease states, other medications, and preferred dosage form (e.g., oral suspension, capsules, or chewable tablets). For example, amoxicillin may not be the best agent to select for the infection. In addition, the dose of amoxicillin can be 500 mg every eight hours for a severe infection or 2 grams as a single dose one hour prior to dental procedures for bacterial endocarditis prophylaxis. Other issues to consider with the antibiotic are dose adjustment for renal impairment and interactions with concomitant medications.

• In addition, a brief review of the search strategy and references reviewed may be included in the response as a confirmation to the comprehensive search conducted
• Compose the response at the requestor's comprehension level